SCHEMBL29329150

SCHEMBL29329150

CCOC(=O)Cc1cc(C(F)F)nn1Cc1ccc(OC)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
UCHL1 P09936 1/20 0.41
PKM P14618 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.39
NPC1 O15118 1/20 0.39
THRB P10828 1/20 0.38
FPR1 P21462 1/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25225321 0.83 MAPT (0.44) MAPTKMT2AMEN1UCHL1PKM
SCHEMBL27165200 0.83 MAPT (0.44) MAPTKMT2AMEN1UCHL1PKM
SCHEMBL30859967 0.73 ALDH1A1 (0.46) MAPTKMT2AUCHL1PKMALDH1A1
SCHEMBL924496 0.72 KMT2A (0.63) KMT2AMEN1ALDH1A1TDP1
SCHEMBL30999701 0.72 S1PR1 (0.41) MAPTKMT2AMEN1UCHL1ALDH1A1
SCHEMBL30999703 0.72 S1PR1 (0.41) MAPTKMT2AMEN1UCHL1ALDH1A1
SCHEMBL27077740 0.72 NPBWR1 (0.44) MAPTKMT2AMEN1UCHL1PKM
SCHEMBL22412886 0.71 MAPT (0.53) MAPTUCHL1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL17476916 0.71 CACNA1H (0.49) MAPTKMT2AMEN1UCHL1
SCHEMBL31511067 0.70 MAPT (0.49) MAPTUCHL1ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4649076-A1 HERBICIDAL PYRAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-19 EP disclosed
WO-2024149676-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-18 WO disclosed
WO-2024149676-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-07-18 WO disclosed