Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652356 | 0.84 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL11279116 | 0.84 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL7056757 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL8252856 | 0.79 | ALDH1A1 (0.73) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL7046856 | 0.78 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL11289476 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL7051937 | 0.75 | HPGD (0.53) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL11276300 | 0.75 | LMNA (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD | |
| SCHEMBL7534562 | 0.75 | ALDH1A1 (0.71) | ALDH1A1HPGDGAAHTTKDM4E | |
| SCHEMBL2075491 | 0.75 | LMNA (0.63) | CYP1A2CYP2C9CYP2C19ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461341-B1 | PROCESS FOR PREPARING A HETEROAROMATIC COMPOUND SUBSTITUTED WITH ONE OR MORE ETHER GROUPS | AGFA GEVAERT (BE) | 2010-01-27 | — | — | EP | disclosed |
| US-6734312-B2 | CONDENSING HYDROXY- GROUP OF A COMPOUND HAVING HETEROAROMATIC NUCLEUS, WITH AN ALCOHOL CONTAINING ONE OR MORE PRIMARY OR SECONDARY ALCOHOL GROUPS, OPTIONALLY USING THE REDOX COUPLE OF A TRIARYL- OR TRIALKYLPHOSPHINE AND AN AZODIOXO-COMPOUND | AGFA-GEVAERT (BE) | 2004-05-11 | — | — | US | disclosed |
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | AGFA-GEVAERT (BE) | 2003-08-28 | — | — | US | disclosed |
| US-5587144-A | Diazine chelating agents for diagnostic imaging | NYCOMED IMAGING AS (NO) | 1996-12-24 | — | — | US | disclosed |
| US-5439668-A | Heterocyclic chelating agents | NYCOMED IMAGING AS (NO) | 1995-08-08 | — | — | US | disclosed |
| EP-0452392-B1 | HETEROCYCLIC CHELATING AGENTS | NYCOMED IMAGING AS (NO) | 1995-04-12 | — | — | EP | disclosed |
| US-5348954-A | Heterocyclic chelating agents | NYCOMED IMAGING AS (NO) | 1994-09-20 | — | — | US | disclosed |
| EP-0452392-A1 | HETEROCYCLIC CHELATING AGENTS. | NYCOMED AS (NO) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990008138-A1 | HETEROCYCLIC CHELATING AGENTS | NYCOMED AS (NO) | 1990-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | ADH1C, ADH1A, CYP2E1 | CYP1A2 19/4885CYP2C9 168/4885CYP2C19 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.