Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329348 | 0.91 | MKNK1 (0.34) | P2RX7TRPC5MKNK1EGFRKDR | |
| SCHEMBL29330204 | 0.91 | P2RX7 (0.39) | P2RX7TRPC5MKNK1EGFRKDR | |
| SCHEMBL29329068 | 0.88 | TRPC5 (0.38) | P2RX7TRPC5MKNK1 | |
| SCHEMBL27123762 | 0.77 | TRPC5 (0.44) | P2RX7TRPC5KDR | |
| SCHEMBL29329821 | 0.77 | TRPC5 (0.35) | TRPC5 | |
| SCHEMBL29329699 | 0.75 | TRPC5 (0.49) | P2RX7TRPC5KDR | |
| SCHEMBL29329558 | 0.74 | TRPC5 (0.42) | P2RX7TRPC5 | |
| SCHEMBL29330501 | 0.70 | MKNK1 (0.36) | P2RX7MKNK1 | |
| SCHEMBL29330999 | 0.70 | TRPC5 (0.43) | P2RX7TRPC5KDR | |
| SCHEMBL27119901 | 0.68 | TRPC5 (0.40) | P2RX7TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |