Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 3/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328686 | 0.91 | P2RX7 (0.36) | MKNK1P2RX7DPP4DPP8DPP7 | |
| SCHEMBL29330913 | 0.80 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL29328354 | 0.78 | ATG7 (0.32) | P2RX7 | |
| SCHEMBL29328670 | 0.77 | TRPC5 (0.34) | P2RX7DPP4DPP8DPP7 | |
| SCHEMBL29329348 | 0.77 | MKNK1 (0.34) | MKNK1P2RX7MAPK14KDM4EMEN1 | |
| SCHEMBL29328871 | 0.70 | GRM2 (0.32) | MAPK14DPP4DPP8DPP7GPR6 | |
| SCHEMBL29329527 | 0.70 | P2RX7 (0.33) | MKNK1P2RX7 | |
| SCHEMBL29330204 | 0.70 | P2RX7 (0.39) | MKNK1P2RX7MAPK14 | |
| SCHEMBL29328518 | 0.70 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL29330275 | 0.70 | MKNK1 (0.48) | MKNK1P2RX7P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |