Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330204 | 0.93 | P2RX7 (0.39) | MKNK1P2RX7MAPK14EGFRKDR | |
| SCHEMBL29329527 | 0.91 | P2RX7 (0.33) | MKNK1P2RX7EGFRKDRTRPC5 | |
| SCHEMBL29329068 | 0.91 | TRPC5 (0.38) | MKNK1P2RX7TRPC5ENPP2 | |
| SCHEMBL27123762 | 0.79 | TRPC5 (0.44) | P2RX7KDRTRPC5 | |
| SCHEMBL29329821 | 0.77 | TRPC5 (0.35) | TRPC5 | |
| SCHEMBL29330501 | 0.77 | MKNK1 (0.36) | MKNK1P2RX7MAPK14KDM4EMEN1 | |
| SCHEMBL29329699 | 0.77 | TRPC5 (0.49) | P2RX7KDRTRPC5 | |
| SCHEMBL29329558 | 0.76 | TRPC5 (0.42) | P2RX7TRPC5 | |
| SCHEMBL29330999 | 0.73 | TRPC5 (0.43) | P2RX7KDRTRPC5 | |
| SCHEMBL29328354 | 0.69 | ATG7 (0.32) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |