Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 3/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 7/20 | 0.37 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330069 | 0.82 | TRPC5 (0.39) | TRPC5TRPC4 | |
| SCHEMBL22412918 | 0.82 | TRPC5 (0.47) | TRPC5TRPC4USP2TSHR | |
| SCHEMBL29329165 | 0.80 | TRPC5 (0.47) | TRPC5TRPC4 | |
| SCHEMBL29329548 | 0.77 | TRPC5 (0.40) | TRPC5TRPC4 | |
| SCHEMBL21807318 | 0.77 | TRPC5 (0.38) | PDE9ATRPC5TRPC4CYP3A4TSHR | |
| SCHEMBL21807393 | 0.76 | TRPC5 (0.52) | TRPC5TRPC4 | |
| SCHEMBL29329977 | 0.75 | P2RX3 (0.45) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL29090279 | 0.73 | TRPC5 (0.37) | TRPC5TRPC4 | |
| SCHEMBL21807174 | 0.73 | TRPC5 (0.52) | TRPC5TRPC4 | |
| SCHEMBL21807248 | 0.73 | TRPC5 (0.65) | TRPC5TRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |