Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330715 | 0.86 | CHRNA7 (0.35) | CHRNA7KCNH2CHEK1SIRT2PPARA | |
| SCHEMBL30938633 | 0.82 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2PPARAPPARD | |
| SCHEMBL30938642 | 0.82 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2PPARAPPARD | |
| SCHEMBL29330952 | 0.82 | SIRT2 (0.35) | CHRNA7CHEK1SIRT2PPARAPPARD | |
| SCHEMBL29333406 | 0.82 | SIRT2 (0.35) | CHRNA7SIRT2PPARAPPARD | |
| SCHEMBL29330428 | 0.79 | ESR1 (0.42) | CHRNA7KCNH2SYKKDRESR1 | |
| SCHEMBL29331084 | 0.78 | SIRT2 (0.35) | CHEK1SIRT2PPARAPPARD | |
| SCHEMBL29329368 | 0.78 | ESR1 (0.41) | TTBK1SIRT2TTBK2ESR1 | |
| SCHEMBL29329365 | 0.78 | MET (0.40) | SYKKDRESR1 | |
| SCHEMBL29328881 | 0.77 | SYK (0.38) | SYKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |