Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331093 | 0.94 | KDM4E (0.35) | IMPDH2RAB9AAPPMETJAK2 | |
| SCHEMBL29331089 | 0.93 | MET (0.37) | IMPDH2APPMETJAK2JAK1 | |
| SCHEMBL29330496 | 0.92 | GAA (0.34) | HTR1AAPPMETPRKAB2PRKAG1 | |
| SCHEMBL30938599 | 0.92 | APP (0.33) | IMPDH2APPMETCYP3A4PRKAB2 | |
| SCHEMBL29330500 | 0.90 | P2RY14 (0.35) | CSNK1A1CSNK1DAPPKDM4EGAA | |
| SCHEMBL29330566 | 0.89 | IMPDH2 (0.50) | IMPDH2METCDC7KDM4EHPGD | |
| SCHEMBL30938624 | 0.88 | CSNK1A1 (0.41) | IMPDH2CSNK1A1CSNK1DABCG2APP | |
| SCHEMBL29330958 | 0.88 | CSNK1A1 (0.41) | IMPDH2CSNK1A1CSNK1DABCG2APP | |
| SCHEMBL30938641 | 0.88 | APP (0.31) | APPMET | |
| SCHEMBL29332698 | 0.84 | GAA (0.35) | IMPDH2HTR1AAPPJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |