Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331093 | 0.93 | KDM4E (0.35) | APPMETKDM4EGAAHPGD | |
| SCHEMBL29330842 | 0.92 | IMPDH2 (0.36) | APPMETKDM4EGAAHPGD | |
| SCHEMBL29330496 | 0.91 | GAA (0.34) | APPMETKDM4EGAAHPGD | |
| SCHEMBL29330500 | 0.89 | P2RY14 (0.35) | APPKDM4EGAAHPGDP2RY14 | |
| SCHEMBL29331089 | 0.88 | MET (0.37) | APPMETIMPDH2 | |
| SCHEMBL30938641 | 0.87 | APP (0.31) | APPMET | |
| SCHEMBL29332698 | 0.83 | GAA (0.35) | APPKDM4EGAAHPGDPRKAB2 | |
| SCHEMBL29330566 | 0.82 | IMPDH2 (0.50) | METKDM4EHPGDMAPTIMPDH2 | |
| SCHEMBL30938642 | 0.81 | SIRT2 (0.35) | APPMETKDRP2RY14 | |
| SCHEMBL30938633 | 0.81 | SIRT2 (0.35) | APPMETKDRP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |