Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330495 | 0.89 | IMPDH2 (0.38) | IMPDH2MAOBEGFRMETAR | |
| SCHEMBL29330842 | 0.89 | IMPDH2 (0.36) | IMPDH2HPGDKDM4ELTA4HPLA2G2A | |
| SCHEMBL30938624 | 0.86 | CSNK1A1 (0.41) | IMPDH2HPGDSMN1; SMN2TRPM8TTBK1 | |
| SCHEMBL29330958 | 0.86 | CSNK1A1 (0.41) | IMPDH2HPGDSMN1; SMN2TRPM8TTBK1 | |
| SCHEMBL29331093 | 0.85 | KDM4E (0.35) | IMPDH2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL29331089 | 0.83 | MET (0.37) | IMPDH2MET | |
| SCHEMBL29330430 | 0.82 | PRKCQ (0.43) | IMPDH2ALDH1A1HPGDMAPTNSD2 | |
| SCHEMBL29330496 | 0.82 | GAA (0.34) | HPGDKDM4EMAPTEGFRTTBK1 | |
| SCHEMBL30938599 | 0.82 | APP (0.33) | IMPDH2HPGDKDM4EMAPTMET | |
| SCHEMBL29330570 | 0.81 | APP (0.36) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |