Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | GLA | P06280 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.62 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.56 |
| ▸ | IL4 | P05112 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841107 | 0.88 | KDM4E (0.82) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29331857 | 0.79 | IL4 (0.77) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL31139657 | 0.78 | KDM4E (1.00) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7505116 | 0.77 | KDM4E (0.84) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL31139650 | 0.76 | KDM4E (0.81) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29332196 | 0.72 | TNKS (0.43) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7553240 | 0.72 | KDM4E (0.76) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3371543 | 0.70 | ADORA1 (0.89) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7510328 | 0.69 | KDM4E (0.71) | KDM4ETDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7509621 | 0.69 | KDM4E (0.71) | KDM4ETDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043621-B2 | Small molecule inhibitors of Interleukin-4 | IL4, IL2, IL4I1 | KDM4E 586/4885TDP1 4759/4885MEN1 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.