SCHEMBL29333670

SCHEMBL29333670

C=CC(=O)N1CCOC[C@H]1c1cc(Cl)cc(-c2cc(N)on2)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SCD5 Q86SK9 1/20 0.33
▸ CCNC P24863 1/20 0.33
▸ CDK8 P49336 1/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30855080 1.00 SCD5 (0.33) SCD5CCNCCDK8MAPK1
SCHEMBL31008618 0.86 MAPK1 (0.34) CCNCCDK8MAPK1
SCHEMBL29333783 0.86 MAPK1 (0.34) CCNCCDK8MAPK1
SCHEMBL31008554 0.85 CCNC (0.35) SCD5CCNCCDK8MAPK1
SCHEMBL29333555 0.85 CCNC (0.35) SCD5CCNCCDK8MAPK1
SCHEMBL31008619 0.84 MAPK1 (0.34) SCD5CCNCCDK8MAPK1
SCHEMBL31008658 0.84 PIK3CA (0.39) CCNCCDK8MAPK1
SCHEMBL31008626 0.84 CCNC (0.38) CCNCCDK8MAPK1
SCHEMBL31008588 0.84 JAK2 (0.35) CCNCCDK8MAPK1
SCHEMBL29333491 0.84 JAK2 (0.35) CCNCCDK8MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 — — US disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226114-A1 INHIBITORS AND USES THEREOF KEAP1, NQO1, NFE2L2 SCD5 2732/4885CCNC 4349/4885CDK8 1776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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