SCHEMBL29335604

SCHEMBL29335604

C=CCN(Cc1ccc(Br)cc1)CC(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 8/20 0.58
LSS P48449 2/20 0.45
CTSK P43235 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAOB P27338 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1D P25100 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR1E P28566 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20871891 0.85 CNR2 (0.40) PYCR1LSSALDH1A1HTR1AADRA2A
SCHEMBL20871892 0.82 RIPK1 (0.46) PYCR1L3MBTL1HTR1AADRA2ADRD2
SCHEMBL22340499 0.81 PYCR1 (0.64) PYCR1LSSKDM4EALDH1A1MAOB
SCHEMBL20871896 0.81 ALDH1A1 (0.49) PYCR1ALDH1A1HTR1AADRA2AADRA2B
SCHEMBL29336098 0.79 PYCR1 (0.60) PYCR1LSSKDM4EALDH1A1MAOB
SCHEMBL29335095 0.77 PYCR1 (0.58) PYCR1LSSKDM4EALDH1A1MAOB
SCHEMBL20871036 0.76 PYCR1 (0.57) PYCR1LSSKDM4EALDH1A1HRH3
SCHEMBL29334681 0.75 PYCR1 (0.56) PYCR1LSSKDM4EALDH1A1HTR1A
SCHEMBL29335264 0.75 PYCR1 (0.55) PYCR1LSSKDM4EALDH1A1MAOB
SCHEMBL29336000 0.75 PYCR1 (0.55) PYCR1LSSKDM4EALDH1A1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707132-B1 NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES UNIV PARIS SACLAY (FR) 2024-07-17 EP disclosed