Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29336098 | 0.86 | PYCR1 (0.60) | PYCR1KDM4EALDH1A1LSSHRH3 | |
| SCHEMBL20871858 | 0.84 | CNR2 (0.49) | PYCR1HRH3HDAC8HDAC6 | |
| SCHEMBL20871036 | 0.83 | PYCR1 (0.57) | PYCR1KDM4EALDH1A1LSSHRH3 | |
| SCHEMBL69821 | 0.82 | PYCR1 (0.69) | PYCR1KDM4EALDH1A1HRH3HDAC8 | |
| SCHEMBL10187442 | 0.82 | PYCR1 (0.69) | PYCR1KDM4EALDH1A1HRH3HDAC8 | |
| SCHEMBL29336000 | 0.82 | PYCR1 (0.55) | PYCR1KDM4EALDH1A1LSSHRH3 | |
| SCHEMBL12126078 | 0.81 | CNR2 (0.50) | KDM4EALDH1A1HRH3MAOB | |
| SCHEMBL29335095 | 0.81 | PYCR1 (0.58) | PYCR1KDM4EALDH1A1LSSHRH3 | |
| SCHEMBL29335604 | 0.81 | PYCR1 (0.58) | PYCR1KDM4EALDH1A1LSSHRH3 | |
| SCHEMBL20871264 | 0.81 | PYCR1 (0.54) | PYCR1KDM4EALDH1A1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | Universite Paris-Saclay (FR) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | ADH1C, ADH1A, ADH5 | PYCR1 1084/4885KDM4E 2452/4885ALDH1A1 179/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | PYCR1 1943/4885KDM4E 2466/4885ALDH1A1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.