Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148906 | 0.94 | — | — | |
| Ethylene SCHEMBL28311644 | 0.84 | ESR2 (0.31) | ESR2 | |
| SCHEMBL6059421 | 0.83 | — | — | |
| Ethylene Glycol SCHEMBL27474186 | 0.83 | ESR2 (0.35) | ESR2TRIM24TRIM33TSHRALDH1A1 | |
| SCHEMBL6317148 | 0.81 | TRIM24 (0.50) | ESR2TRIM24TRIM33TSHRALDH1A1 | |
| SCHEMBL22235926 | 0.79 | ALDH1A1 (0.52) | ESR2TRIM24TRIM33TSHRALDH1A1 | |
| Ethylene SCHEMBL8915548 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL7791809 | 0.78 | ESR2 (0.35) | ESR2TRIM24TRIM33TSHRALDH1A1 | |
| SCHEMBL7791812 | 0.78 | ESR2 (0.35) | ESR2TRIM24TRIM33TSHRALDH1A1 | |
| SCHEMBL19339444 | 0.78 | ESR2 (0.35) | ESR2TRIM24TRIM33TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850200-A | Method for industrialized production of 4-hydroxyl cyclohexanone | XI AN CAIJING OPTO ELECTRICAL SCIENCE & TECHNOLOGY CO LTD | 2013-01-02 | — | — | CN | claimed |
| WO-2024121013-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | disclosed |
| EP-3517536-B1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3517536-A1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10253019-B2 | Tank-binding kinase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180370955-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2018-12-27 | — | — | US | disclosed |
| US-10040781-B2 | Tank-binding kinase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-3197884-A1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| CN-106715419-A | Aminotriazine derivatives as TANK-binding kinase inhibitor compounds | 吉利德科学公司 | 2017-05-24 | — | — | CN | disclosed |
| US-9434693-B2 | Substituted pyrazoles as N-type calcium channel blockers | JANSSEN PHARMACEUTICA NV (BE) | 2016-09-06 | — | — | US | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |
| US-5595992-A | Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-21 | — | — | US | disclosed |
| CN-1076929-A | Some cycloalkyl and azacycloalkyl pyrrolopyrimidines; The γ-An Jidingsuan brain receptor ligands that one class is new | NEUROGEN CORP (US) | 1993-10-06 | — | — | CN | disclosed |
| CN-1074903-A | The six hydrogen azepine ketone and the tetrahydro benzo azepine ketone that replace | PFIZER (US) | 1993-08-04 | — | — | CN | disclosed |
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4366172-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4143156-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4115589-A | 1-(HYDROXYMETHYL)-4-(DIALKYLAMINO)-4-PHENYLCYCLOHEXANOLS, ANALGESICS | THE UPJOHN COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180370955-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | ESR2 2241/4885TRIM24 516/4885TRIM33 1630/4885 |
| US-10253019-B2 | Tank-binding kinase inhibitor compounds | TBKBP1, TNKS1BP1, TNKS | ESR2 2241/4885TRIM24 516/4885TRIM33 1630/4885 |
| US-10040781-B2 | Tank-binding kinase inhibitor compounds | TBKBP1, TNKS1BP1, TNKS | ESR2 2241/4885TRIM24 516/4885TRIM33 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.