Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285551 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29337702 | 0.92 | USP2 (0.43) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29338295 | 0.91 | KDM4E (0.40) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29338529 | 0.90 | TUBB4A (0.39) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29336710 | 0.90 | F10 (0.45) | KDM4EHSD17B10 | |
| SCHEMBL30285558 | 0.90 | TUBB4A (0.39) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29338297 | 0.88 | KDM4E (0.38) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL31108617 | 0.88 | L3MBTL1 (0.44) | L3MBTL1KDM4EHSD17B10RHEBUSP2 | |
| SCHEMBL29336928 | 0.87 | F10 (0.40) | KDM4EHSD17B10RHEBTUBB4ATUBB | |
| SCHEMBL31108646 | 0.87 | ALOX5 (0.45) | KDM4EHSD17B10RHEBSMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239784-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239784-A1 | INDOLE COMPOUNDS AND METHODS OF USE | CFTR, INMT, IDO1 | L3MBTL1 3265/4885KDM4E 4001/4885HSD17B10 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.