Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29339653 | 1.00 | DRD3 (0.35) | DRD3DRD4HRH3KDM1ADRD1 | |
| SCHEMBL29341898 | 0.86 | PDK1 (0.40) | DRD3DRD4HRH3KDM1ADRD1 | |
| SCHEMBL23323133 | 0.82 | DRD4 (0.38) | DRD3DRD4HRH3DRD1 | |
| SCHEMBL22693302 | 0.79 | DRD4 (0.30) | DRD4 | |
| SCHEMBL25565642 | 0.78 | DRD3 (0.51) | DRD3DRD4 | |
| SCHEMBL25565643 | 0.78 | DRD3 (0.51) | DRD3DRD4 | |
| SCHEMBL9801156 | 0.78 | DRD3 (0.51) | DRD3DRD4 | |
| SCHEMBL11576109 | 0.75 | DRD3 (0.42) | DRD3DRD4HRH3DRD1 | |
| SCHEMBL9921758 | 0.75 | PIK3CD (0.44) | DRD3DRD4HRH3 | |
| SCHEMBL24951149 | 0.75 | DRD3 (0.39) | DRD3DRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | DRD3 3477/4885DRD4 4346/4885HRH3 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.