Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344810 | 0.82 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL29340146 | 0.72 | BTK (0.36) | BTK | |
| SCHEMBL29340337 | 0.70 | BTK (0.43) | BTKERN1MAPK1 | |
| SCHEMBL29339015 | 0.68 | BTK (0.38) | BTKMAPK1 | |
| SCHEMBL29338952 | 0.67 | BTK (0.37) | BTKMAPK1 | |
| SCHEMBL27059272 | 0.61 | POLB (0.47) | BTK | |
| SCHEMBL27063663 | 0.61 | BTK (0.37) | BTKMAPK1 | |
| SCHEMBL18765597 | 0.61 | BTK (0.45) | BTK | |
| SCHEMBL18766028 | 0.60 | MAPK1 (0.69) | MAPK1 | |
| SCHEMBL18765652 | 0.59 | MAPK1 (0.68) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |