Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29338952 | 0.86 | BTK (0.37) | BTKPDK1 | |
| SCHEMBL29339015 | 0.78 | BTK (0.38) | BTKPDK1 | |
| SCHEMBL29340337 | 0.76 | BTK (0.43) | BTKPDK1 | |
| SCHEMBL29339899 | 0.72 | BTK (0.32) | BTK | |
| SCHEMBL29340129 | 0.70 | MAPK1 (0.40) | — | |
| SCHEMBL17589018 | 0.66 | — | — | |
| SCHEMBL27059272 | 0.66 | POLB (0.47) | BTK | |
| SCHEMBL18794084 | 0.65 | HIF1A (0.39) | BTKPDK1 | |
| SCHEMBL7539390 | 0.64 | AHR (0.48) | BTK | |
| SCHEMBL19100395 | 0.64 | APP (0.40) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |