Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29338952 | 0.83 | BTK (0.37) | BTKPDK1MAPK1 | |
| SCHEMBL29340146 | 0.78 | BTK (0.36) | BTKPDK1 | |
| SCHEMBL29339151 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL29340129 | 0.74 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL29340337 | 0.70 | BTK (0.43) | BTKPDK1ALDH1A1MAPTMEN1 | |
| SCHEMBL29339899 | 0.68 | BTK (0.32) | BTKMAPK1 | |
| SCHEMBL29339013 | 0.67 | ROCK1 (0.37) | MEN1KMT2ALTA4H | |
| SCHEMBL18765563 | 0.67 | BTK (0.42) | BTKPDK1MAPTKDM4EPDK2 | |
| SCHEMBL18765934 | 0.67 | MAPK1 (0.58) | MAPK1 | |
| SCHEMBL18794084 | 0.66 | HIF1A (0.39) | BTKPDK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |