Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29340146 | 0.86 | BTK (0.36) | BTKPDK1 | |
| SCHEMBL29339015 | 0.83 | BTK (0.38) | BTKMAPK1PDK1 | |
| SCHEMBL29340129 | 0.74 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL29339151 | 0.73 | SMN1; SMN2 (0.52) | MAPK1 | |
| SCHEMBL29340337 | 0.73 | BTK (0.43) | BTKMAPK1PDK1 | |
| SCHEMBL23742570 | 0.71 | F2 (0.33) | F2F10 | |
| SCHEMBL29339899 | 0.67 | BTK (0.32) | BTKMAPK1 | |
| SCHEMBL18794084 | 0.67 | HIF1A (0.39) | BTKMAPK1PDK1 | |
| SCHEMBL18793713 | 0.65 | MAPK1 (0.68) | MAPK1 | |
| SCHEMBL27059272 | 0.64 | POLB (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |