Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551797 | 0.78 | KCNQ3 (0.42) | BTKALDH1A1PDK1PDK2PDK3 | |
| SCHEMBL30036996 | 0.78 | KCNQ3 (0.42) | BTKALDH1A1PDK1PDK2PDK3 | |
| SCHEMBL31592748 | 0.76 | BTK (0.45) | BTKPDK1PDK2PDK3PDK4 | |
| SCHEMBL29340146 | 0.76 | BTK (0.36) | BTKPDK1 | |
| SCHEMBL27059272 | 0.75 | POLB (0.47) | BTKALDH1A1LMNAGAAKDM4E | |
| SCHEMBL30919676 | 0.74 | BTK (0.43) | BTKALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL27263191 | 0.74 | BTK (0.43) | BTKALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL29676954 | 0.73 | BTK (0.46) | BTKPDK1PDK2PDK3PDK4 | |
| SCHEMBL18766101 | 0.73 | BTK (0.46) | BTKPDK1PDK2PDK3PDK4 | |
| SCHEMBL7539390 | 0.73 | AHR (0.48) | BTKALDH1A1LMNAMAPTKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |