Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29343655 | 0.89 | HTR2A (0.37) | HTR2AHTR2CMAPTL3MBTL1KDM4E | |
| SCHEMBL29340007 | 0.88 | LIG1 (0.39) | HTR2AMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29343659 | 0.85 | NPC1 (0.40) | HTR2AHTR2CMAPTL3MBTL1KDM4E | |
| SCHEMBL29340192 | 0.80 | SMN1; SMN2 (0.33) | HTR2AHTR2CKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29340147 | 0.80 | POLB (0.35) | MAPTKDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL29340183 | 0.79 | MAPT (0.40) | HTR2AHTR2CMAPTL3MBTL1KDM4E | |
| SCHEMBL29340126 | 0.77 | KDM4E (0.41) | MAPTKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29339894 | 0.77 | ADCY10 (0.37) | HTR2AMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29343103 | 0.77 | ALDH1A1 (0.39) | HTR2AMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29343102 | 0.73 | ALDH1A1 (0.39) | L3MBTL1KDM4EALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | UACA, ADCYAP1R1, ADCY1 | HTR2A 3883/4885HTR2C 3853/4885MAPT 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.