Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551797 | 1.00 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL30036275 | 0.88 | KMO (0.40) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL25551800 | 0.88 | KMO (0.40) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL25551795 | 0.83 | KMO (0.59) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL30035839 | 0.83 | KMO (0.59) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL12813119 | 0.78 | AXL (0.49) | KMONISCHCHRNA7PDK1PDK2 | |
| SCHEMBL30919676 | 0.78 | BTK (0.43) | BTKPDK1PDK2PDK4RPS6KA5 | |
| SCHEMBL31281284 | 0.78 | CYP11B2 (0.53) | — | |
| SCHEMBL29340337 | 0.78 | BTK (0.43) | BTKKMOPDK1PDK2PDK3 | |
| SCHEMBL27263191 | 0.78 | BTK (0.43) | BTKPDK1PDK2PDK4RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |