Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 3/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 8/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | TFDP2 | Q14188 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676954 | 0.85 | BTK (0.46) | BTKPDK1PDK2PDK4PDK3 | |
| SCHEMBL18766101 | 0.85 | BTK (0.46) | BTKPDK1PDK2PDK4PDK3 | |
| SCHEMBL30036996 | 0.77 | KCNQ3 (0.42) | BTKKMOPDK1PDK2PDK4 | |
| SCHEMBL25551797 | 0.77 | KCNQ3 (0.42) | BTKKMOPDK1PDK2PDK4 | |
| SCHEMBL22097892 | 0.76 | CDH1 (0.45) | BTK | |
| SCHEMBL30919676 | 0.76 | BTK (0.43) | BTKPDK1PDK2PDK4HSP90AA1 | |
| SCHEMBL29340337 | 0.76 | BTK (0.43) | BTKKMOPDK1PDK2PDK4 | |
| SCHEMBL27263191 | 0.76 | BTK (0.43) | BTKPDK1PDK2PDK4HSP90AA1 | |
| SCHEMBL24852574 | 0.76 | PDK1 (0.48) | PDK1PDK2PDK4PDK3HSP90AA1 | |
| SCHEMBL31557673 | 0.76 | PDK1 (0.48) | PDK1PDK2PDK4PDK3HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |