Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119766 | 0.79 | ALDH1A1 (0.37) | KCNH2HRH1HRH4HRH3ABCB1 | |
| SCHEMBL2545151 | 0.69 | HTR6 (0.47) | HTR1AHTR7 | |
| SCHEMBL10078400 | 0.69 | HRH1 (0.40) | KCNH2HRH1HRH4HRH3HDAC2 | |
| SCHEMBL28869984 | 0.65 | ADRB1 (0.48) | HTR1AHTR7ALDH1A1 | |
| SCHEMBL10077099 | 0.64 | HTR6 (0.49) | HTR1AHTR7BRD4ALDH1A1BRD2 | |
| SCHEMBL5029237 | 0.64 | ADRB1 (0.47) | ALDH1A1 | |
| SCHEMBL3942886 | 0.62 | ALDH1A1 (0.43) | HRH1HRH4HRH3HTR1AHTR7 | |
| SCHEMBL28222649 | 0.62 | HRH4 (0.44) | HRH4HRH3ALDH1A1 | |
| SCHEMBL2876202 | 0.60 | ADRB1 (0.52) | KCNH2HRH1HRH4HRH3HDAC2 | |
| SCHEMBL27960523 | 0.59 | HTR7 (0.50) | HRH3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781292-B1 | EXTENDED RELEASE FORMULATION OF 3-AMINO-8-(1-PIPERAZINYL)-2H-1BENZOPYRAN-2-ONE | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2010-09-22 | — | — | EP | claimed |