SCHEMBL29344183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4172887	0.81	LMNA (0.54)	CYP1A2CYP2A6LMNAHTTPTPN22
	SCHEMBL20967276	0.81	CYP1A2 (0.50)	CYP1A2CYP2A6TRPM4ALDH1A1HPGD
	SCHEMBL24713061	0.79	CYP1A2 (0.50)	CYP1A2CYP2A6TRPM4ALDH1A1HPGD
	SCHEMBL30364741	0.79	TRPM4 (0.50)	CYP1A2CYP2A6LMNAHTTPTPN22
	SCHEMBL29680396	0.79	TRPM4 (0.56)	CYP1A2PTPN22TRPM4NQO2CASP6
	SCHEMBL4247740	0.79	PTPN22 (0.45)	CYP1A2PTPN22TRPM4NQO2CASP6
	SCHEMBL15485758	0.79	NQO1 (0.50)	CYP1A2CYP2A6LMNAHTTPTPN22
	SCHEMBL631989	0.79	TRPM4 (0.56)	CYP1A2PTPN22TRPM4NQO2CASP6
	SCHEMBL50068	0.79	TRPM4 (0.50)	CYP1A2CYP2A6LMNAHTTPTPN22
	SCHEMBL27486426	0.76	CYP1A2 (0.45)	CYP1A2CYP2A6LMNAHTTPTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.