SCHEMBL29346102

SCHEMBL29346102

O=C1C=CC(=O)C1c1ccc(C2C(=O)C=CC2=O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.36
MAPT P10636 4/20 0.36
CYP3A4 P08684 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36
HTR2B P41595 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 2/20 0.32
MAOA P21397 1/20 0.32
PTGS2 P35354 1/20 0.32
MAPK10 P53779 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14665742 0.87 KDM1A (0.43) HTR2BKMT2ASMN1; SMN2
SCHEMBL14665739 0.87 MEN1 (0.54) MAPTCYP3A4LMNACYP1A2HTR2B
SCHEMBL10297367 0.84 ALDH1A1 (0.40) TP53CYP3A4LMNAMAPK1MEN1
SCHEMBL14665734 0.81 MAOA (0.58) TP53MAPTCYP3A4LMNAMAPK1
SCHEMBL10297368 0.77 MAPT (0.36) TP53MAPTCYP3A4LMNACYP1A2
SCHEMBL14095538 0.70 MAPT (0.45) TP53MAPTCYP3A4LMNACYP1A2
SCHEMBL14665716 0.69 KDM1A (0.50) MAPTLMNAHTR2BMEN1KMT2A
SCHEMBL12201063 0.65
Bromide SCHEMBL11510071 0.62 HSP90AA1 (0.35)
Bromide SCHEMBL11508917 0.62 HSP90AA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240088-A1 FLAME RETARDANT POLYMERS AND PROCESSES FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-07-18 US disclosed
US-20240240088-A1 FLAME RETARDANT POLYMERS AND PROCESSES FOR PRODUCING AND USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-07-18 US disclosed