Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201063 | 0.74 | — | — | |
| SCHEMBL12235919 | 0.60 | — | — | |
| SCHEMBL11355322 | 0.59 | — | — | |
| SCHEMBL801782 | 0.59 | S100A4 (0.36) | HSP90AA1 | |
| SCHEMBL801296 | 0.59 | ALDH1A1 (0.31) | HSP90AA1 | |
| SCHEMBL13019275 | 0.59 | ALDH1A1 (0.31) | HSP90AA1 | |
| SCHEMBL17131854 | 0.59 | ALDH1A1 (0.31) | HSP90AA1 | |
| SCHEMBL7088503 | 0.59 | — | — | |
| SCHEMBL1091985 | 0.57 | — | — | |
| SCHEMBL18917295 | 0.55 | KDM4E (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170452-A | Dye composition containing diphenylamine and polyhydroxybenzene | L'OREAL (FR) | 1979-10-09 | — | — | US | disclosed |