Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 14/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348449 | 0.86 | CREBBP (0.46) | CREBBPBRD4 | |
| SCHEMBL29348200 | 0.82 | F10 (0.36) | — | |
| SCHEMBL29348769 | 0.82 | F10 (0.36) | — | |
| SCHEMBL31068259 | 0.80 | CRBN (0.44) | FFAR2CREBBPBRD4 | |
| SCHEMBL31637574 | 0.80 | CRBN (0.44) | FFAR2CREBBPBRD4 | |
| SCHEMBL29348360 | 0.78 | PDCD1LG2 (0.39) | CREBBPBRD4 | |
| SCHEMBL29348413 | 0.77 | CD274 (0.37) | — | |
| SCHEMBL29348456 | 0.76 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL29348526 | 0.75 | ROCK2 (0.35) | CREBBPBRD4SRD5A1 | |
| SCHEMBL29349028 | 0.75 | CNR2 (0.36) | CREBBPBRD4SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |