SCHEMBL29348295

SCHEMBL29348295

O=C1C[C@@H]2CCC[C@@H]2C1I

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14635952 0.68 HSD11B1 (0.31)
SCHEMBL11761907 0.68 HTR1A (0.30) HTR1A
SCHEMBL13219285 0.68 CA1 (0.38) HTR1A
SCHEMBL19576446 0.67
SCHEMBL8348252 0.65
SCHEMBL13451146 0.65
SCHEMBL3152983 0.65
SCHEMBL1634001 0.65
SCHEMBL11834734 0.65 F2R (0.39)
SCHEMBL21595432 0.65 PRSS1 (0.50) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151547-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed