Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30920991 | 0.79 | LMNA (0.38) | CTSSCTSKKMT2ALMNACTSL | |
| SCHEMBL22904099 | 0.78 | LMNA (0.39) | CTSSCTSKKMT2ALMNACTSB | |
| SCHEMBL29348328 | 0.77 | CTSS (0.35) | CTSSCTSKKMT2ACTSBCTSL | |
| SCHEMBL31068163 | 0.77 | CTSS (0.35) | CTSSCTSKKMT2ACTSBCTSL | |
| SCHEMBL15268526 | 0.75 | CTSS (0.41) | CTSSCTSKKMT2ACTSBCTSL | |
| SCHEMBL26633408 | 0.73 | CTSS (0.43) | CTSSCTSKKMT2ACTSBMEN1 | |
| SCHEMBL21656168 | 0.73 | CTSL (0.43) | CTSSCTSKKMT2ALMNACTSB | |
| SCHEMBL22904302 | 0.72 | TBXA2R (0.37) | CTSSCTSKCTSBGAA | |
| SCHEMBL630897 | 0.72 | CTSS (0.36) | CTSSCTSKKMT2ALMNACTSL | |
| SCHEMBL24548383 | 0.72 | CTSK (0.41) | CTSSCTSKKMT2ALMNACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |