Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348448 | 0.86 | FFAR2 (0.34) | CREBBPBRD4 | |
| SCHEMBL31068121 | 0.81 | CREBBP (0.47) | CREBBPBRD4HPGDMAPK1ALDH1A1 | |
| SCHEMBL29348783 | 0.81 | CREBBP (0.47) | CREBBPBRD4HPGDMAPK1ALDH1A1 | |
| SCHEMBL29348412 | 0.80 | CREBBP (0.48) | CREBBPBRD4HPGDMAPK1ALDH1A1 | |
| SCHEMBL29348360 | 0.77 | PDCD1LG2 (0.39) | CREBBPBRD4HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29348200 | 0.76 | F10 (0.36) | — | |
| SCHEMBL29348769 | 0.76 | F10 (0.36) | — | |
| SCHEMBL29349028 | 0.76 | CNR2 (0.36) | CREBBPBRD4 | |
| SCHEMBL29348526 | 0.76 | ROCK2 (0.35) | CREBBPBRD4 | |
| SCHEMBL29348513 | 0.74 | GRM2 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |