Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068370 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRRAB9ANPC1LMNA | |
| SCHEMBL29348360 | 0.77 | PDCD1LG2 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL29348448 | 0.76 | FFAR2 (0.34) | — | |
| SCHEMBL29348449 | 0.74 | CREBBP (0.46) | SMN1; SMN2TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL29348769 | 0.70 | F10 (0.36) | — | |
| SCHEMBL29348200 | 0.70 | F10 (0.36) | — | |
| SCHEMBL29348776 | 0.69 | CNR2 (0.32) | RAB9AALDH1A1 | |
| SCHEMBL29349028 | 0.68 | CNR2 (0.36) | — | |
| SCHEMBL29348526 | 0.68 | ROCK2 (0.35) | — | |
| SCHEMBL31068131 | 0.68 | CRBN (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |