Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068174 | 1.00 | PIK3CD (0.42) | PIK3CDPIK3CBDDB1CRBNFABP4 | |
| SCHEMBL29348682 | 0.92 | FABP4 (0.49) | DDB1CRBNFABP4BRD4CREBBP | |
| SCHEMBL31068269 | 0.92 | FABP4 (0.49) | DDB1CRBNFABP4BRD4CREBBP | |
| SCHEMBL31068306 | 0.84 | CREBBP (0.45) | DDB1CRBNCREBBPLCKBTK | |
| SCHEMBL31068205 | 0.79 | DRD2 (0.43) | DDB1CRBNCREBBPABL1NPC1 | |
| SCHEMBL29348689 | 0.79 | DDB1 (0.44) | DDB1CRBNBRD4CREBBPNPC1 | |
| SCHEMBL31068156 | 0.79 | DDB1 (0.44) | DDB1CRBNBRD4CREBBPNPC1 | |
| SCHEMBL31068335 | 0.78 | PGR (0.50) | DDB1CRBNBRD4CREBBP | |
| SCHEMBL31068353 | 0.78 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL29348370 | 0.78 | DDB1 (0.46) | DDB1CRBNBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |