Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12333052 | 0.89 | GSK3A (0.42) | KDM4ETDP1L3MBTL1CA2CA9 | |
| SCHEMBL142716 | 0.84 | NPC1 (0.46) | KDM4EMGLLHPGDHSD17B10ALDH1A1 | |
| SCHEMBL31334475 | 0.82 | CBL (0.45) | KDM4EPOLBTDP1L3MBTL1MEN1 | |
| SCHEMBL10305669 | 0.82 | ALDH1A1 (0.53) | KDM4ERXFP1CA1CA2CA5A | |
| SCHEMBL142926 | 0.82 | KIF11 (0.47) | KDM4EPOLBTDP1MGLLHPGD | |
| SCHEMBL6116854 | 0.82 | KIF11 (0.47) | KDM4ETDP1L3MBTL1TRPV1HPGD | |
| SCHEMBL141047 | 0.82 | MIF (0.46) | KDM4EMGLLHPGDHSD17B10ALDH1A1 | |
| SCHEMBL10079418 | 0.82 | KDM4E (0.37) | KDM4EPOLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13075264 | 0.82 | ALDH1A1 (0.41) | KDM4ETDP1L3MBTL1KMT2ARXFP1 | |
| SCHEMBL143208 | 0.81 | ALDH1A1 (0.56) | KDM4EPOLBRXFP1TRPV1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |