Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348653 | 0.83 | CRBN (0.36) | P2RX7FNTAPGGT1B | |
| SCHEMBL31068216 | 0.83 | CRBN (0.36) | P2RX7FNTAPGGT1B | |
| SCHEMBL29348526 | 0.77 | ROCK2 (0.35) | — | |
| SCHEMBL29349028 | 0.75 | CNR2 (0.36) | P2RX7DRD4 | |
| SCHEMBL29348200 | 0.74 | F10 (0.36) | — | |
| SCHEMBL29348769 | 0.74 | F10 (0.36) | — | |
| SCHEMBL29348449 | 0.72 | CREBBP (0.46) | — | |
| SCHEMBL29348776 | 0.72 | CNR2 (0.32) | — | |
| SCHEMBL31068143 | 0.71 | CRBN (0.35) | P2RX7FNTAPGGT1B | |
| SCHEMBL29348519 | 0.71 | HCRTR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |