Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.63 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.63 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | HTR3B | O95264 | 1/20 | 0.63 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.63 |
| ▸ | CHRNG | P07510 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894032 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14113737 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29429735 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL166107 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29350350 | 0.95 | ALDH1A1 (0.91) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL4538641 | 0.95 | ALDH1A1 (0.91) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19958134 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| Nicotine SCHEMBL1206396 | 0.80 | ALDH1A1 (0.83) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| (+/-)Nicotine SCHEMBL28179049 | 0.80 | ALDH1A1 (0.83) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23181386 | 0.78 | CHRNA7 (0.67) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084338-A | N-nitrosamine mixed solution standard substance and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084340-A | N-nitrosonornicotine (NNN) purity standard substance, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12638424-B2 | Method for determining tobacco-specific nitrosamines (TSNAs) in cigarette smoke using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) | YUNNAN ACADEMY OF TOBACCO AGRICULTURAL SCIENCES (CN) | 2026-05-26 | — | — | US | claimed |
| EP-2935588-B1 | TOBACCO SPECIFIC NITROSAMINE REDUCTION IN PLANTS | PHILIP MORRIS PRODUCTS SA (CH) | 2026-03-25 | — | — | EP | claimed |
| US-12575601-B2 | Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols | MAGI'S LAB SRL (IT) | 2026-03-17 | — | — | US | claimed |
| EP-4684652-A1 | AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-28 | — | — | EP | claimed |
| EP-4423039-B1 | POLYMER FREE AND LOW ODOR UREASE INHIBITOR FORMULATION WITH IMPROVED STORAGE STABILITY ON UREA | BASF SE (DE) | 2025-09-17 | — | — | EP | claimed |
| EP-4593641-A1 | RECONSTITUTED TOBACCO SUBSTRATE FOR AEROSOL DELIVERY DEVICE | Nicoventures Trading Limited (GB) | 2025-08-06 | — | — | EP | claimed |
| EP-4311440-B1 | FIBROUS FILTRATION MATERIAL FOR ELECTRONIC SMOKING ARTICLE | RAI STRATEGIC HOLDINGS INC (US) | 2025-07-02 | — | — | EP | claimed |
| US-20250026697-A1 | POLYMER FREE AND LOW ODOR UREASE INHIBITOR FORMULATION WITH IMPROVED STORAGE STABILITY ON UREA | BASF SE (DE) | 2025-01-23 | — | — | US | claimed |
| US-11377665-B2 | Composition and methods for producing tobacco plants and products having increased phenylalanine and reduced tobacco-specific nitrosamines (TSNAs) | ALTRIA CLIENT SERVICES LLC (US) | 2022-07-05 | — | — | US | claimed |
| CN-114641574-A | Method for modifying alkaloid content in plants | 英美烟草(投资)有限公司 | 2022-06-17 | — | — | CN | claimed |
| US-20220170035-A1 | METHOD | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2022-06-02 | — | — | US | claimed |
| EP-3994267-A1 | METHOD FOR MODIFYING ALKALOID CONTENT IN PLANTS | British American Tobacco (Investments) Limited (GB) | 2022-05-11 | — | — | EP | claimed |
| EP-3993611-A1 | METHOD FOR MODULATING THE ALKALOID CONTENT OF A TOBACCO PLANT | British American Tobacco (Investments) Limited (GB) | 2022-05-11 | — | — | EP | claimed |
| CN-114402077-A | Method | 英美烟草(投资)有限公司 | 2022-04-26 | — | — | CN | claimed |
| EP-3979820-A1 | LIQUID TOBACCO EXTRACT, METHOD FOR MAKING AND AEROSOL-GENERATING ARTICLES COMPRISING SUCH | Philip Morris Products S.A. (CH) | 2022-04-13 | — | — | EP | claimed |
| CN-114341360-A | Method for modulating alkaloid content of tobacco plants | 英美烟草(投资)有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-110958840-B | Fibrous filter material for electronic smoking articles | 莱战略控股公司 | 2022-04-12 | — | — | CN | claimed |
| EP-3969595-A1 | METHOD | British American Tobacco (Investments) Limited (GB) | 2022-03-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12575601-B2 | Reduction of amines and nitrosamines in cigarette smoke vapors through a filter functionalized with olive tree polyphenols | NNMT, NAT1, NAT10 | ALDH1A1 441/4885CHRNA7 467/4885CHRNB2 858/4885 |
| US-12638424-B2 | Method for determining tobacco-specific nitrosamines (TSNAs) in cigarette smoke using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) | TYMS, NNMT, SRMS | ALDH1A1 2748/4885CHRNA7 251/4885CHRNB2 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.