Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.63 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.63 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | HTR3B | O95264 | 1/20 | 0.63 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.63 |
| ▸ | CHRNG | P07510 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894032 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14113737 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29429735 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29349441 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL29350350 | 0.95 | ALDH1A1 (0.91) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL4538641 | 0.95 | ALDH1A1 (0.91) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19958134 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| Nicotine SCHEMBL1206396 | 0.80 | ALDH1A1 (0.83) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| (+/-)Nicotine SCHEMBL28179049 | 0.80 | ALDH1A1 (0.83) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23181386 | 0.78 | CHRNA7 (0.67) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084340-A | N-nitrosonornicotine (NNN) purity standard substance, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084338-A | N-nitrosamine mixed solution standard substance and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12628862-B2 | Liquid tobacco extract, method for making and aerosol-generating articles comprising such | PHILIP MORRIS PRODUCTS S.A. (CH) | 2026-05-19 | — | — | US | claimed |
| US-12544025-B2 | Determining a biological tissue structural marker for diagnosis of a disease | Arion Diagnostics, Inc. (US) | 2026-02-10 | — | — | US | claimed |
| US-20260026543-A1 | TOBACCO FLAVOURED DRY POWDER FORMULATION | PHILIP MORRIS PRODUCTS SA (CH) | 2026-01-29 | — | — | US | claimed |
| US-12497627-B2 | BZIP transcription factors regulate conversion of nicotine to nornicotine | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2025-12-16 | — | — | US | claimed |
| CN-116083293-B | Bacillus bailii DX-32 for efficiently degrading nitrite and TSNAs and application thereof | 中国烟草总公司郑州烟草研究院 | 2025-04-18 | — | — | CN | claimed |
| EP-3482641-B1 | TOBACCO RAW MATERIAL | BRITISH AMERICAN TOBACCO SWEDEN AB (SE) | 2025-01-01 | — | — | EP | claimed |
| EP-4442128-A1 | SMOKELESS TOBACCO POUCH | R. J. Reynolds Tobacco Company (US) | 2024-10-09 | — | — | EP | claimed |
| CN-115736307-B | Preparation method and application of ginger charcoal nano-class component with scorched fragrance | 昆明理工大学 | 2024-09-13 | — | — | CN | claimed |
| WO-2007072231-A2 | METAL-CONTAINING NANOWIRES PREPARED USING MESOPOROUS MOLECULAR SIEVES AS TEMPLATES, AND THEIR USE IN SMOKING ARTICLES | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-06-28 | — | — | WO | claimed |
| US-20070113862-A1 | Oxidant/catalyst nanoparticles to reduce tobacco smoke constituents such as carbon monoxide | PHILIP MORRIS USA INC. | 2007-05-24 | — | — | US | claimed |
| US-7017585-B2 | Oxidant/catalyst nanoparticles to reduce tobacco smoke constituents such as carbon monoxide | PHILIP MORRIS USA INC. (US) | 2006-03-28 | — | — | US | claimed |
| US-20050133047-A1 | Smoking articles and filters with carbon-coated molecular sieve sorbent | PHILIP MORRIS USA INC. | 2005-06-23 | — | — | US | claimed |
| US-20050133048-A1 | Amphiphile-modified sorbents in smoking articles and filters | PHILIP MORRIS USA INC. | 2005-06-23 | — | — | US | claimed |
| US-20050133054-A1 | Composite mesoporous/microporous materials and their use in smoking articles for removing certain gas phase constituents from tobacco smoke | PHILIP MORRIS USA INC. | 2005-06-23 | — | — | US | claimed |
| WO-2004041008-A1 | OXIDANT/CATALYST NANOPARTICLES TO REDUCE TOBACCO SMOKE CONSTITUENTS SUCH AS CARBON MONOXIDE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2004-05-21 | — | — | WO | claimed |
| US-20040025895-A1 | Oxidant/catalyst nanoparticles to reduce tobacco smoke constituents such as carbon monoxide | PHILIP MORRIS USA INC. | 2004-02-12 | — | — | US | claimed |
| US-20030131859-A1 | Oxidant/catalyst nanoparticles to reduce tobacco smoke constituents such as carbon monoxide | PHILIP MORRIS USA INC. | 2003-07-17 | — | — | US | claimed |
| US-5803081-A | Tobacco and related products | REGENT COURT TECHNOLOGIES (US) | 1998-09-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12628862-B2 | Liquid tobacco extract, method for making and aerosol-generating articles comprising such | NDUFB10, EXOSC10, NDUFB7 | ALDH1A1 990/4885CHRNA7 84/4885CHRNB2 242/4885 |
| US-20260026543-A1 | TOBACCO FLAVOURED DRY POWDER FORMULATION | CTNND1, IL17A, TAS2R20 | ALDH1A1 726/4885CHRNA7 121/4885CHRNB2 205/4885 |
| US-12544025-B2 | Determining a biological tissue structural marker for diagnosis of a disease | KRT18, DSP, COL14A1 | ALDH1A1 1034/4885CHRNA7 2645/4885CHRNB2 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.