Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclobenzaprine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 5/20 | 0.97 |
| ▸ | HTR2C known ✓ | P28335 | 5/20 | 0.97 |
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 8/20 | 0.97 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.97 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.97 |
| ▸ | HTR2B | P41595 | 6/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.97 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.97 |
| ▸ | DRD2 | P14416 | 6/20 | 0.97 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.97 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.97 |
| ▸ | DRD3 | P35462 | 6/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.97 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclobenzaprine SCHEMBL4964925 | 1.00 | LMNA (1.00) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL41376 | 1.00 | LMNA (1.00) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL4606463 | 0.98 | LMNA (0.97) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL7654526 | 0.98 | HRH1 (1.00) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL38527 | 0.98 | HRH1 (1.00) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL29520569 | 0.98 | HRH1 (1.00) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL1649752 | 0.95 | HRH1 (0.93) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL17812812 | 0.92 | LMNA (0.85) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL17812696 | 0.90 | HRH1 (0.84) | LMNAPMP22MEN1KMT2AAPEX1 | |
| Cyclobenzaprine SCHEMBL29015268 | 0.89 | HRH1 (0.82) | LMNAPMP22MEN1KMT2AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122093894-A | Cooperative communication relay selection method and system for non-identical interference environment | — | 2026-05-26 | — | — | CN | claimed |
| CN-122052354-A | Coil arrangement design method and system of multi-relay wireless energy transmission structure | 国网四川省电力公司阿坝供电公司 | 2026-05-15 | — | — | CN | claimed |
| CN-121585927-A | Test fixture, signal test method and electronic equipment | 苏州元脑智能科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-114268993-B | Multi-subsystem nested coding caching method and system for heterogeneous user caching capacity | 杭州电子科技大学 | 2025-06-17 | — | — | CN | claimed |
| CN-120075790-A | Hidden communication method and system based on outdated channel state information and relay selection | 江苏科技大学 | 2025-05-30 | — | — | CN | claimed |
| CN-114302458-B | Multi-subsystem weighted interference elimination coding caching method and system in multi-relay interference network | 杭州电子科技大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119827968-A | Multi-type multi-path relay performance tester | 三门核电有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-114828149-B | Collaborative spatial modulation system performance analysis method based on multi-relay forwarding | 南京航空航天大学 | 2025-03-25 | — | — | CN | claimed |
| CN-119651937-A | Multi-relay wireless power transmission system based on switch capacitor and use method thereof | 陕西科技大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119603648-A | Optimal Bayesian and preemptive data attack method for multi-hop and multi-relay wireless sensor network | 龙门实验室 | 2025-03-11 | — | — | CN | claimed |
| CN-114143237-A | Extensible router startup and shutdown automatic test method and system | 深圳市奇虎智能科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-109890031-B | Multi-relay non-orthogonal multiple access system safe transmission method based on artificial noise | 重庆邮电大学 | 2022-03-01 | — | — | CN | claimed |
| CN-111342877-B | Multi-relay wireless data transmission control method, communication system and terminal equipment | 深圳先进技术研究院 | 2022-02-22 | — | — | CN | claimed |
| CN-114035034-A | Relay adhesion diagnosis method and device based on coil current characteristics | 苏州正力芯控电子有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-110381473-B | Network coding assisted D2D communication multi-relay selection method | 哈尔滨工业大学（威海） | 2022-02-11 | — | — | CN | claimed |
| CN-111641991-B | Multi-relay two-hop network secure transmission method based on data caching | 西北工业大学 | 2022-02-08 | — | — | CN | claimed |
| CN-114019360-A | Multi-relay diagnostic system and method | 智新控制系统有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-114024640-A | Robust relay node selection method in full-duplex energy collection relay system | 西安邮电大学 | 2022-02-08 | — | — | CN | claimed |
| CN-113972631-A | Intelligent alarm method and system for relay protection master station | 北京四方继保工程技术有限公司 | 2022-01-25 | — | — | CN | claimed |
| CN-113962179-A | Method and device for optimizing multi-relay coil coupling structure of remote WPT system | 广西电网有限责任公司电力科学研究院 | 2022-01-21 | — | — | CN | claimed |