Rotenone

Rotenone

SCHEMBL29351552

C=C(C)C1Cc2c(ccc3c2OC2COc4cc(OC)c(OC)cc4C2C3=O)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 11/20 1.00
MAPT P10636 8/20 1.00
SMN1; SMN2 Q16637 8/20 1.00
ALDH1A1 P00352 5/20 1.00
KDM4E B2RXH2 5/20 1.00
TDP1 Q9NUW8 5/20 1.00
CYP2C19 P33261 4/20 1.00
LMNA P02545 4/20 1.00
MAPK1 P28482 4/20 1.00
TP53 P04637 4/20 1.00
USP2 O75604 4/20 1.00
TSHR P16473 3/20 1.00
MT-ND4 P03905 3/20 1.00
CYP2C9 P11712 2/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
CYP1A2 P05177 2/20 1.00
HPGD P15428 2/20 1.00
GMNN O75496 1/20 1.00
ABCB11 O95342 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rotenone SCHEMBL20152380 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL29388856 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL13845713 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL9815546 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL13926662 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL42253 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL19019920 1.00 CYP3A4 (1.00) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL5490007 0.99 CYP3A4 (0.98) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL7142434 0.97 CYP3A4 (0.95) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E
Rotenone SCHEMBL8386940 0.96 CYP3A4 (0.93) CYP3A4MAPTSMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076959-A Processing technology of alloy rod wire 2026-05-26 CN claimed
CN-122094360-A Perovskite light-emitting module and preparation method thereof 2026-05-26 CN claimed
CN-122085229-A Multi-radar interference resource allocation method based on physical projection reinforcement learning 2026-05-26 CN claimed
CN-224263074-U RhizoTron x square root system phenotype is high spectral imaging analysis system 北京易科泰生态技术有限公司 2026-05-19 CN claimed
EP-3801044-B1 HIGH-PAYLOAD, NON-POROUS, ENZYME-CONTAINING COATED GRANULES DANISCO US INC (US) 2026-04-29 EP claimed
US-12611762-B2 System with a power tool and an energy supply device, and interface, and energy supply device HILTI AKTIENGESELLSCHAFT (LI) 2026-04-28 US claimed
US-12608540-B1 Breadth scoring using relevant document term frequency Moat Metrics, Inc. (US) 2026-04-21 US claimed
CN-119514228-B Multistage cohesive force unit analysis method considering composite material resin enrichment region and fiber bridging influence mechanism 武汉理工大学 2026-02-27 CN claimed
CN-121582318-A Method and system for measuring weight of yak body ruler based on DeepLabCut and depth information 青海大学 2026-02-27 CN claimed
US-12552007-B2 Systems that comprise power tools and energy supply devices, and energy supply device HILTI AKTIENGESELLSCHAFT (LI) 2026-02-17 US claimed
CN-112903442-B Method for testing I-type fracture toughness of bonding interface of composite material bonding structure 北京市科学技术研究院分析测试研究所(北京市理化分析测试中心) 2022-07-26 CN claimed
US-20220187491-A1 METHOD TO CALCULATE THE EFFECTIVE HYDRAULIC APERTURE AND PERMEABILITY OF ROCK FRACTURES SAUDI ARABIAN OIL COMPANY (SA) 2022-06-16 US claimed
CN-114202590-B Color calibration method and system based on calibration model, intelligent terminal and medium 北京中科慧眼科技有限公司 2022-05-17 CN claimed
US-20220148718-A1 SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR PREDICTIVE MAINTENANCE BAYER HEALTHCARE LLC 2022-05-12 US claimed
WO-2022071146-A1 ADSORPTION HEAT EXCHANGER ダイキン工業株式会社 2022-04-07 WO claimed
CN-110300884-B Optical particle sensor module 通快光电器件有限公司 2022-03-29 CN claimed
WO-2022061356-A2 METHODS AND APPARATUSES FOR DETERMINING A POSITION OF A SECURITY TAG Sensormatic Electronics, LLC (US) 2022-03-24 WO claimed
CN-114202590-A Color calibration method and system based on calibration model, intelligent terminal and medium 北京中科慧眼科技有限公司 2022-03-18 CN claimed
US-20220084380-A1 METHODS AND APPARATUSES FOR DETERMINING A POSITION OF A SECURITY TAG Sensormatic Electronics, LLC 2022-03-17 US claimed
CN-110268245-B Laser sensor module for particle density detection 通快光电器件有限公司 2022-03-04 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552007-B2 Systems that comprise power tools and energy supply devices, and energy supply device CNTN1, TESK2, EPHA2 CYP3A4 4241/4885MAPT 1867/4885SMN1; SMN2 538/4885
US-12608540-B1 Breadth scoring using relevant document term frequency DKK1, PWWP2B, MDM2 CYP3A4 4204/4885MAPT 3937/4885SMN1; SMN2 1099/4885
US-12611762-B2 System with a power tool and an energy supply device, and interface, and energy supply device TESK2, TESK1, ADIPOR2 CYP3A4 4148/4885MAPT 3771/4885SMN1; SMN2 2646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.