SCHEMBL29352010

SCHEMBL29352010

O=C1Cc2ccccc2N1Cc1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
PKM P14618 1/20 0.54
LMNA P02545 1/20 0.48
XIAP P98170 1/20 0.46
BRD4 O60885 2/20 0.45
HTR7 P34969 6/20 0.45
POLB P06746 1/20 0.44
DRD2 P14416 2/20 0.44
DRD4 P21917 1/20 0.44
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
HTR1A P08908 4/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
CHRM1 P11229 1/20 0.43
DRD5 P21918 1/20 0.42
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27662072 0.81 KDM4C (0.46) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL41923 0.77 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL30597487 0.76 POLB (0.73) ALDH1A1KMT2AMEN1HTR7POLB
SCHEMBL578257 0.76 POLB (0.73) ALDH1A1KMT2AMEN1HTR7POLB
SCHEMBL27376464 0.74 ATAD2 (0.58) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL30806763 0.74 ATAD2 (0.58) ALDH1A1KMT2AMEN1PKMLMNA
Pyrimidine SCHEMBL28042274 0.74 POLB (0.60) ALDH1A1KMT2AMEN1HTR7POLB
SCHEMBL9122848 0.73 GSK3A (0.60) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL23068173 0.72 KMT2A (0.63) ALDH1A1KMT2AMEN1PKMLMNA
SCHEMBL5394439 0.72 HTR7 (0.53) ALDH1A1KMT2AMEN1HTR7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113966271-A Agent capable of reacting with or removing oxygen molecules 李蓁蓁 2022-01-21 CN disclosed