SCHEMBL29356967

SCHEMBL29356967

CCC1(O)CC(OC2CC(N(C)C)C(OC3CC4OC5CC(=O)C(C)OC5OC4C(C)O3)C(C)O2)c2c(O)c3c(c(O)c2C1O)C(=O)c1cccc(O)c1C3=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.57
MMP2 P08253 3/20 0.57
HTR2B P41595 2/20 0.57
MEN1 O00255 11/20 0.55
KMT2A Q03164 11/20 0.55
RECQL P46063 7/20 0.55
MAPT P10636 6/20 0.55
SMN1; SMN2 Q16637 6/20 0.55
USP2 O75604 5/20 0.55
CYP3A4 P08684 4/20 0.55
TP53 P04637 2/20 0.55
HBB P68871 1/20 0.55
THRB P10828 9/20 0.50
BLM P54132 9/20 0.50
KDM4E B2RXH2 4/20 0.50
CASP1 P29466 2/20 0.50
HSD17B10 Q99714 2/20 0.50
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
S100A4 P26447 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504362 0.94 PTGS1 (0.56) PTGS1MMP2HTR2BMEN1KMT2A
Rodorubicin SCHEMBL8693 0.92 MEN1 (0.58) PTGS1MMP2HTR2BMEN1KMT2A
Rodorubicin SCHEMBL29352818 0.92 MEN1 (0.58) PTGS1MMP2HTR2BMEN1KMT2A
SCHEMBL29403905 0.92 PTGS1 (0.54) PTGS1MMP2HTR2BMEN1KMT2A
SCHEMBL29884381 0.89 PTGS1 (0.67) PTGS1MMP2HTR2BMEN1KMT2A
SCHEMBL29557045 0.89 MMP2 (0.58) PTGS1MMP2HTR2BMEN1KMT2A
Aclacinomycin B SCHEMBL2500101 0.87 MMP2 (0.74) PTGS1MMP2HTR2BMEN1KMT2A
Aclacinomycin B SCHEMBL29561911 0.87 MMP2 (0.74) PTGS1MMP2HTR2BMEN1KMT2A
SCHEMBL29381144 0.85 PTGS1 (0.50) PTGS1MMP2HTR2BMEN1KMT2A
SCHEMBL29467023 0.84 PTGS1 (0.77) PTGS1MMP2HTR2BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2024-10-17 US claimed
US-11345956-B2 Methods and compositions related to prostate cancer therapeutics THE JOHNS HOPKINS UNIVERSITY (US) 2022-05-31 US claimed
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF IBIO, INC. (US) 2026-05-28 US disclosed
EP-4748449-A2 USE OF SHORT CHAIN FATTY ACIDS IN CANCER PREVENTION Temple University Of The Commonwealth System Of Higher Education (US) 2026-05-27 EP disclosed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CITY OF HOPE (US) 2026-05-26 US disclosed
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS THE TRUSTEES OF THE UNIV OF PENNSYLVANIA (US) 2026-05-21 US disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
WO-2026102111-A1 METHODS FOR TREATING OR PREVENTING PROSTATE CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-15 WO disclosed
US-11241423-B2 Antiproliferative compounds and methods of use thereof CELGENE CORPORATION (US) 2022-02-08 US disclosed
US-11241500-B2 HSP90-targeting conjugates and formulations thereof TARVEDA THERAPEUTICS, INC. (US) 2022-02-08 US disclosed
US-11241455-B2 Methods of treating disease by metabolic control of T-cell differentiation THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) 2022-02-08 US disclosed
WO-2022023772-A1 ANTAGONIST COMPOUNDS AdoRx Therapeutics Limited (GB) 2022-02-03 WO disclosed
US-20220031641-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION PHARMATROPHIX, INC. 2022-02-03 US disclosed
US-20220031853-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-03 US disclosed
EP-3941905-A1 SUMO INHIBITOR COMPOUNDS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2022-01-26 EP disclosed
EP-3941919-A1 PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AS INHIBITORS OF ENDORIBONUCLEASE INOSITOL REQUIRING ENZYME I (IRE I ALPHA) FOR THE TREATMENT OF CANCER DISEASES Genentech, Inc. (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC3, HDAC1, HDAC4 PTGS1 4049/4885MMP2 490/4885HTR2B 1731/4885
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS LCP2, CD47, CD4 PTGS1 3298/4885MMP2 3675/4885HTR2B 4534/4885
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CD47, IGLV6-57, STING1 PTGS1 4034/4885MMP2 3828/4885HTR2B 3935/4885
US-20220031641-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION CHRM3, CHAT, CHRM5 PTGS1 671/4885MMP2 2013/4885HTR2B 89/4885
US-11241423-B2 Antiproliferative compounds and methods of use thereof MCL1, MKI67, BAX PTGS1 704/4885MMP2 894/4885HTR2B 4194/4885
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 PTGS1 4874/4885MMP2 3686/4885HTR2B 2754/4885
US-11241500-B2 HSP90-targeting conjugates and formulations thereof HSP90AB1, HSP90AA1, HSP90B1 PTGS1 2126/4885MMP2 740/4885HTR2B 4307/4885
US-20220031853-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF HSP90AB1, HSP90AA1, HSP90B1 PTGS1 2126/4885MMP2 740/4885HTR2B 4307/4885
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF MSTN, MST1R, MYOF PTGS1 4780/4885MMP2 3212/4885HTR2B 3233/4885
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC1, HDAC7, HDAC5 PTGS1 2311/4885MMP2 177/4885HTR2B 2266/4885
US-11241455-B2 Methods of treating disease by metabolic control of T-cell differentiation GOT1, IL17A, OGDH PTGS1 223/4885MMP2 4298/4885HTR2B 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.