Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772026 | 0.98 | FOLH1 (0.45) | OPRM1OPRD1FOLH1TASP1KEAP1 | |
| SCHEMBL29771973 | 0.96 | FOLH1 (0.44) | OPRM1OPRD1FOLH1TASP1KEAP1 | |
| SCHEMBL29360974 | 0.96 | OPRM1 (0.46) | OPRM1OPRD1FOLH1TASP1KEAP1 | |
| SCHEMBL29772133 | 0.94 | FOLH1 (0.49) | OPRM1OPRD1FOLH1KEAP1OPRK1 | |
| SCHEMBL29772030 | 0.93 | EGFR (0.47) | OPRM1OPRD1FOLH1OPRK1EGFR | |
| SCHEMBL29353451 | 0.93 | FOLH1 (0.44) | OPRM1OPRD1FOLH1TASP1KEAP1 | |
| SCHEMBL29493327 | 0.92 | OPRM1 (0.45) | OPRM1OPRD1TASP1KEAP1OPRK1 | |
| SCHEMBL31487991 | 0.92 | OPRM1 (0.47) | OPRM1OPRD1FOLH1TASP1OPRK1 | |
| SCHEMBL30069105 | 0.91 | BACE1 (0.46) | EGFRBACE1CTSDTFPI | |
| SCHEMBL29777713 | 0.91 | TFPI (0.49) | OPRM1OPRD1OPRK1EGFRGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12221494-B2 | Short synthetic peptides and their uses for treating retinal degenerative diseases and/or tissue injuries | MACKAY MEMORIAL HOSPITAL (TW) | 2025-02-11 | — | — | US | disclosed |
| US-20220204559-A1 | SHORT SYNTHETIC PEPTIDES AND THEIR USES FOR TREATING RETINAL DEGENERATIVE DISEASES AND/OR TISSUE INJURIES | MACKAY MEMORIAL HOSPITAL (TW) | 2022-06-30 | — | — | US | disclosed |