SCHEMBL29771973

SCHEMBL29771973

CC(C)C[C@H](NC(=O)[C@@H](N)CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.44
▸ OPRM1 P35372 4/20 0.43
▸ OPRD1 P41143 4/20 0.43
▸ OPRK1 P41145 3/20 0.43
▸ EGFR P00533 1/20 0.42
▸ BACE1 P56817 3/20 0.41
▸ KEAP1 Q14145 1/20 0.40
▸ TASP1 Q9H6P5 1/20 0.40
▸ CTSB P07858 1/20 0.40
▸ GLO1 Q04760 1/20 0.39
▸ CTSD P07339 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29772026 0.98 FOLH1 (0.45) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL29772029 0.96 OPRM1 (0.46) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL29772133 0.94 FOLH1 (0.49) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL29772030 0.93 EGFR (0.47) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL29493327 0.92 OPRM1 (0.45) OPRM1OPRD1OPRK1EGFRBACE1
SCHEMBL29360974 0.92 OPRM1 (0.46) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL31487991 0.92 OPRM1 (0.47) FOLH1OPRM1OPRD1OPRK1TASP1
SCHEMBL31194150 0.90 FOLH1 (0.49) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL30905707 0.89 GRIN2D (0.46) FOLH1OPRM1OPRD1OPRK1EGFR
SCHEMBL29353451 0.89 FOLH1 (0.44) FOLH1OPRM1OPRD1OPRK1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12221494-B2 Short synthetic peptides and their uses for treating retinal degenerative diseases and/or tissue injuries MACKAY MEMORIAL HOSPITAL (TW) 2025-02-11 — — US disclosed
US-20220204559-A1 SHORT SYNTHETIC PEPTIDES AND THEIR USES FOR TREATING RETINAL DEGENERATIVE DISEASES AND/OR TISSUE INJURIES MACKAY MEMORIAL HOSPITAL (TW) 2022-06-30 — — US disclosed
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