Ribose (Furanose)

Ribose (Furanose)

SCHEMBL2935366

Cc1nc(N)c2[nH]cnc2n1.OC[C@H]1OC(O)[C@@H](O)[C@@H]1O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.42
GDA Q9Y2T3 1/20 0.42
LMNA P02545 2/20 0.37
GMNN O75496 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
NFKB1 P19838 1/20 0.37
DNMT1 P26358 1/20 0.37
THPO P40225 1/20 0.37
MTOR P42345 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
BLM P54132 1/20 0.37
HBB P68871 1/20 0.37
PMP22 Q01453 1/20 0.37
HIF1A Q16665 3/20 0.36
NT5E P21589 1/20 0.36
CDK1 P06493 2/20 0.35
CCNB1 P14635 2/20 0.35
CCNA2 P20248 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Diaminopurine SCHEMBL2934952 0.88 PDPK1 (0.59) PDPK1GDALMNAGMNNALDH1A1
2,6-Diaminopurine SCHEMBL10774603 0.88 PDPK1 (0.59) PDPK1GDALMNAGMNNALDH1A1
2,6-Diaminopurine SCHEMBL6241914 0.88 PDPK1 (0.59) PDPK1GDALMNAGMNNALDH1A1
Ribose (Furanose) SCHEMBL4284369 0.86 HIF1A (0.46) PDPK1GDALMNAGMNNALDH1A1
Ribose (Furanose) SCHEMBL17275115 0.81 MGMT (0.38) PDPK1GDALMNAHIF1ANT5E
Adenine SCHEMBL580228 0.81 PI4KA (0.58) LMNAALDH1A1HTTRAB9AHIF1A
Adenine SCHEMBL7746165 0.81 PI4KA (0.58) LMNAALDH1A1HTTRAB9AHIF1A
Adenine SCHEMBL7624128 0.81 PI4KA (0.58) LMNAALDH1A1HTTRAB9AHIF1A
Adenine SCHEMBL38386 0.81 PI4KA (0.58) LMNAALDH1A1HTTRAB9AHIF1A
Dextrose SCHEMBL7886725 0.80 PI4KA (0.56) LMNAALDH1A1HTTRAB9AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060094869-A1 Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside MITSUI CHEMICALS, INC. (JP) 2006-05-04 US claimed
US-20020193314-A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside MITSUI CHEMICALS, INC. (JP) 2002-12-19 US claimed
EP-1178051-A2 PROCESS FOR SELECTIVELY PRODUCING 1-PHOSPHORYLATED SUGAR DERIVATIVE ANOMER AND PROCESS FOR PRODUCING NUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2002-02-06 EP claimed
JP-55045625-A None JP disclosed
EP-1925675-B1 Process for production of nucleoside compound MITSUI CHEMICALS INC (JP) 2010-02-03 EP disclosed
EP-1338654-B1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
EP-1925675-A1 Process for production of nucleoside compound Mitsui Chemicals, Inc. (JP) 2008-05-28 EP disclosed
US-20060094869-A1 Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside MITSUI CHEMICALS, INC. (JP) 2006-05-04 US disclosed
US-7038039-B2 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside MITSUI CHEMICALS, INC. (JP) 2006-05-02 US disclosed
EP-1179598-B1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
US-20040219646-A1 Process for producing nucleoside compound MITSUI CHEMICALS, INC. (JP) 2004-11-04 US disclosed
CN-1476484-A Process for producing nucleoside compound 三井化学株式会社 2004-02-18 CN disclosed
EP-1338654-A1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-08-27 EP disclosed
US-20020193314-A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside MITSUI CHEMICALS, INC. (JP) 2002-12-19 US disclosed
EP-1179598-A1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND Mitsui Chemicals, Inc. (JP) 2002-02-13 EP disclosed
EP-1178051-A2 PROCESS FOR SELECTIVELY PRODUCING 1-PHOSPHORYLATED SUGAR DERIVATIVE ANOMER AND PROCESS FOR PRODUCING NUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2002-02-06 EP disclosed
JP-S5545625-A 2-METHYL-N6-SUBSTITUTED ADENINE-ARABINOSIDE AND ITS PREPARATION AJINOMOTO CO INC 1980-03-31 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094869-A1 Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside PNP, MTAP, GALE PDPK1 253/4885GDA 248/4885LMNA 3037/4885
US-20020193314-A1 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside PNP, GALE, MTAP PDPK1 191/4885GDA 247/4885LMNA 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.