Adenine

Adenine

SCHEMBL580228

Nc1ncnc2nc[nH]c12.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 3/20 0.58
PI4K2B Q8TCG2 3/20 0.58
PI4K2A Q9BTU6 3/20 0.58
PI4KB Q9UBF8 3/20 0.58
LMNA P02545 1/20 0.58
DRD3 P35462 1/20 0.58
XDH P47989 1/20 0.58
LRRK2 Q5S007 1/20 0.58
HIF1A Q16665 2/20 0.48
DOT1L Q8TEK3 3/20 0.43
ADORA3 P0DMS8 2/20 0.43
DPP4 P27487 1/20 0.43
MEN1 O00255 1/20 0.43
SLC28A1 O00337 1/20 0.43
MAP3K7 O43318 1/20 0.43
SLC28A2 O43868 1/20 0.43
GAPDH P04406 1/20 0.43
MAPK1 P28482 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL38386 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7746165 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7624128 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Dextrose SCHEMBL7886725 0.99 PI4KA (0.56) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL8605925 0.84 ADK (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL12542065 0.84 HSD17B10 (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL1531264 0.84 HSD17B10 (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL17824409 0.84 ADK (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL7680729 0.84 CYP3A4 (0.39) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL831005 0.84 CYP3A4 (0.39) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024243-A1 Fine Dry Particulate Adenosine Compositions and Topical Formulations Including the Same LABORATORY SKIN CARE, INC. 2024-01-25 US claimed
CN-114236012-A High performance liquid chromatography analysis method for coenzyme I content detection and application thereof 上海蔚之星生物科技有限公司 2022-03-25 CN claimed
WO-2020230981-A2 ATOPIC DERMATITIS ALLEVIATING AGENT COMPOSITION, ATOPIC DERMATITIS ALLEVIATING AGENT, AND PREPARATION METHOD THEREFOR 오가닉브릿지 주식회사 2020-11-19 WO claimed
US-5397706-A Serum-free basal and culture medium for hematopoietic and leukemia cells CORREA PAULO N (CA) 1995-03-14 US claimed
WO-1993009220-A1 CELL CULTURE MEDIUM CORREA PAULO N (CA) 1993-05-13 WO claimed
JP-56142298-A None JP disclosed
JP-56142297-A None JP disclosed
JP-56142299-A None JP disclosed
JP-56142296-A None JP disclosed
JP-56142295-A None JP disclosed
JP-56142294-A None JP disclosed
US-12350352-B2 Composition for surface modification LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2025-07-08 US disclosed
EP-0354638-A2 Use of adenosine and its derivatives in diagnosis MEDCO RESEARCH INC (US) 1990-02-14 EP disclosed
EP-0058563-A1 Lyophilized phosphorylated nucleosides ens BIO LOGICALS INC. (CA) 1982-08-25 EP disclosed
JP-S56142295-A ADENOSINE DERIVATIVE AND ITS PREPARATION WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed
JP-S56142294-A ADENOSINE DERIVATIVE AND ITS PREPARATION WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed
JP-S56142296-A ADENOSINE DERIVATIVE AND ITS PREPARATION WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed
JP-S56142298-A OLIGONUCLEOTIDE DERIVATIVE AND ITS PREPARATION WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed
JP-S56142297-A OLIGONUCLEOTIDE DERIVATIVE AND ITS PREPARATION WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed
JP-S56142299-A PREPARATION OF OLIGONUCLEOTIDE WAKUNAGA YAKUHIN KK 1981-11-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350352-B2 Composition for surface modification CUTA, PTMS, DNMT1 PI4KA 2543/4885PI4K2B 2673/4885PI4K2A 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.