Adenine

Adenine

SCHEMBL38386

Nc1ncnc2nc[nH]c12.OC[C@H]1OC(O)[C@@H](O)[C@@H]1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 3/20 0.58
PI4K2B Q8TCG2 3/20 0.58
PI4K2A Q9BTU6 3/20 0.58
PI4KB Q9UBF8 3/20 0.58
LMNA P02545 1/20 0.58
DRD3 P35462 1/20 0.58
XDH P47989 1/20 0.58
LRRK2 Q5S007 1/20 0.58
HIF1A Q16665 2/20 0.48
DOT1L Q8TEK3 3/20 0.43
ADORA3 P0DMS8 2/20 0.43
DPP4 P27487 1/20 0.43
MEN1 O00255 1/20 0.43
SLC28A1 O00337 1/20 0.43
MAP3K7 O43318 1/20 0.43
SLC28A2 O43868 1/20 0.43
GAPDH P04406 1/20 0.43
MAPK1 P28482 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL580228 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7746165 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL7624128 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBLMNA
Dextrose SCHEMBL7886725 0.99 PI4KA (0.56) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL8605925 0.84 ADK (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL12542065 0.84 HSD17B10 (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL1531264 0.84 HSD17B10 (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL17824409 0.84 ADK (0.40) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL7680729 0.84 CYP3A4 (0.39) PI4KAPI4K2BPI4K2API4KBLMNA
Ribose (Furanose) SCHEMBL831005 0.84 CYP3A4 (0.39) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2593 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083840-A1 METHODS FOR ABLATING MYELOID DERIVED SUPPRESSOR CELLS USING NEO-201 ANTIBODY PREC BIOLOGICS INC (US) 2026-03-26 US claimed
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2025034898-A1 GASTRIC CANCER PATIENT CLASSIFICATION AND METHODS OF TREATMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-13 WO claimed
CN-119403836-A Methods for eliminating myeloid-derived suppressor cells using NEO-201 antibodies 精密生物制品股份有限公司 2025-02-07 CN claimed
EP-4499710-A1 METHODS FOR ABLATING MYELOID DERIVED SUPPRESSOR CELLS USING NEO-201 ANTIBODY Precision Biologics, Inc. (US) 2025-02-05 EP claimed
US-20240400714-A1 METHODS AND COMPOSITIONS FOR TARGETING TREG CELLS PREC BIOLOGICS INC (US) 2024-12-05 US claimed
US-20240384003-A1 METHODS AND COMPOSITIONS FOR TREATING HEMATOLOGICAL MALIGNANCIES PREC BIOLOGICS INC (US) 2024-11-21 US claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
CN-112041343-B Methods and compositions for targeting Treg cells 精密生物制品股份有限公司 2024-08-30 CN claimed
US-12037410-B2 Methods and compositions for targeting Treg cells PRECISION BIOLOGICS, INC. (US) 2024-07-16 US claimed
EP-0437563-B1 BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES DEBIO RECH PHARMA SA (CH) 1995-02-22 EP claimed
US-5276020-A Viricides with glycoside structure EFAMOL HOLDINGS PLC (GB) 1994-01-04 US claimed
EP-0197718-B1 New medicaments for topical use FIDIA SPA (IT) 1993-12-15 EP claimed
WO-1993023094-A1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M.U.R.S.T., ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH (IT) 1993-11-25 WO claimed
WO-1993018763-A1 COMPOSITIONS OF N-(PHOSPHONOACETYL)-L-ASPARTIC ACID AND METHODS OF THEIR USE AS BROAD SPECTRUM ANTIVIRALS U.S. BIOSCIENCE, INC. (US) 1993-09-30 WO claimed
EP-0555898-A2 Medicaments for non-topical use FIDIA S.p.A. (IT) 1993-08-18 EP claimed
WO-1992018517-A1 METHOD OF TREATING OR PREVENTING HEPATITIS B VIRUS YALE UNIVERSITY (US) 1992-10-29 WO claimed
US-4736024-A Process for preparing salt of hyaluronic acid with a pharmaceutically active substance FIDIA, S.P.A. (IT) 1988-04-05 US claimed
EP-0197718-A2 New medicaments for topical use FIDIA S.p.A. (IT) 1986-10-15 EP claimed
EP-0189629-A1 Method of treatment of viral diseases in plants utilizing ribavirin VIRATEK, INC. (US) 1986-08-06 EP claimed