Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 17/20 | 0.52 |
| ▸ | CETP | P11597 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818149 | 0.92 | CACNA1G (0.51) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL29746466 | 0.92 | CACNA1G (0.51) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL545966 | 0.90 | CACNA1G (0.50) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL3005488 | 0.89 | CACNA1G (0.49) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL25375270 | 0.82 | CACNA1G (0.53) | CACNA1GCACNA1BCACNA1CTACR1CETP | |
| SCHEMBL19950236 | 0.81 | CLK1 (0.45) | CACNA1GCACNA1BCACNA1C | |
| SCHEMBL22771190 | 0.78 | RIPK1 (0.43) | CACNA1GCACNA1BCACNA1C | |
| SCHEMBL3158285 | 0.78 | TACR1 (0.57) | TACR1 | |
| SCHEMBL12435665 | 0.78 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6678261 | 0.77 | CETP (0.43) | CACNA1GCACNA1BCACNA1CTACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993991-B1 | PROCESS FOR THE PREPARATION OF 3,5-BIS (TRIFLUOROMETHYL)-N-METHYLBENZYLAMINE | MITENI SPA (IT) | 2010-09-22 | — | — | EP | disclosed |
| US-7514431-B2 | Piperidinyl cyclopentyl aryl benzylamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514431-B2 | Piperidinyl cyclopentyl aryl benzylamide modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1993991-A2 | PROCESS FOR THE PREPARATION OF 3,5-BIS (TRIFLUOROMETHYL)-N-METHYLBENZYLAMINE | MITENI S.p.A. (IT) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007107818-A2 | PROCESS FOR THE PREPARATION OF 3,5-BIS (TRIFLUOROMETHYL)-N-METHYLBENZYLAMINE | MITENI S.P.A. (IT) | 2007-09-27 | — | — | WO | disclosed |