Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 7/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 8/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545966 | 0.88 | CACNA1G (0.50) | CETPCACNA1GCACNA1BCACNA1CTACR1 | |
| SCHEMBL6681863 | 0.82 | GRM2 (0.39) | GRM2 | |
| SCHEMBL27385426 | 0.80 | TACR1 (0.42) | TACR1IDO1 | |
| SCHEMBL6677408 | 0.80 | CETP (0.42) | CETPCACNA1GCACNA1BCACNA1CGRM2 | |
| SCHEMBL6676867 | 0.79 | CETP (0.40) | CETPCACNA1GCACNA1BCACNA1CGRM2 | |
| SCHEMBL2935441 | 0.77 | CACNA1G (0.55) | CETPCACNA1GCACNA1BCACNA1CTACR1 | |
| SCHEMBL7247305 | 0.76 | GRM2 (0.43) | GRM2 | |
| SCHEMBL31609076 | 0.76 | CACNA1B (0.38) | CETPCACNA1GCACNA1BCACNA1CTACR1 | |
| SCHEMBL10200705 | 0.76 | CACNA1H (0.49) | CACNA1BCACNA1CGRM2TACR1 | |
| SCHEMBL7944783 | 0.75 | GRM2 (0.44) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |